Condition library
Rheumatic and autoimmune conditions
Start here if you have a new diagnosis or are trying to make sense of symptoms. Each guide covers what the condition is, how it’s diagnosed and treated, and how to live well with it.
Inflammatory arthritis
5 guides
Axial Spondyloarthritis
Inflammatory arthritis of the spine and sacroiliac joints, typically starting before age 45 with back pain that improves with movement.
Enteropathic Arthritis
Inflammatory arthritis linked to Crohn’s disease or ulcerative colitis, affecting the limbs, the spine or both.
Psoriatic Arthritis
Inflammatory arthritis that affects some people with psoriasis, involving joints, tendons, nails and sometimes the spine.
Reactive Arthritis
Joint inflammation that develops a few weeks after a gut or genital infection.
Rheumatoid Arthritis
A long-term autoimmune disease where the immune system attacks the lining of the joints, most often in the hands, wrists and feet.
Autoimmune & connective tissue
7 guides
Antiphospholipid Syndrome
An autoimmune condition where antibodies make the blood more likely to clot, causing clots in veins or arteries and pregnancy complications.
Dermatomyositis
An autoimmune disease that inflames muscles and skin, causing weakness near the hips and shoulders and a distinctive rash.
Polymyositis
An inflammatory muscle disease that causes gradual weakness in the muscles closest to the trunk.
Relapsing Polychondritis
A rare autoimmune disease that inflames cartilage in the ears, nose, airways and joints.
Sjögren’s Disease
An autoimmune disease that targets moisture-producing glands, causing dry eyes and dry mouth, and sometimes affecting joints, nerves and organs.
Systemic Lupus Erythematosus
An autoimmune disease that can affect the skin, joints, kidneys, blood and other organs, with periods of flares and calm.
Systemic Sclerosis
An autoimmune disease that causes thickening and hardening of the skin and can affect blood vessels, lungs, heart, kidneys and gut.
Vasculitis & polymyalgia
7 guides
Behçet’s Disease
A rare inflammatory disease of blood vessels that causes recurrent mouth and genital ulcers and can affect the eyes, skin, joints and brain.
Eosinophilic Granulomatosis with Polyangiitis
A rare vasculitis in people with asthma that involves high levels of eosinophils, a type of white blood cell.
Giant Cell Arteritis
Inflammation of large arteries, especially in the head, that can cause sudden vision loss if not treated quickly. It occurs almost only after age 50.
Granulomatosis with Polyangiitis
A form of ANCA-associated vasculitis that inflames small blood vessels, often in the sinuses, lungs and kidneys.
Microscopic Polyangiitis
A small-vessel ANCA-associated vasculitis that most often affects the kidneys and lungs.
Polymyalgia Rheumatica
An inflammatory condition causing pain and stiffness in the shoulders, neck and hips, almost always after age 50.
Takayasu Arteritis
A rare large-vessel vasculitis that inflames the aorta and its main branches, mostly in women under 40.
Crystal arthritis
2 guides
Calcium Pyrophosphate Deposition Disease
Arthritis caused by calcium pyrophosphate crystals in cartilage, which can trigger sudden gout-like attacks, usually in older adults.
Gout
A common inflammatory arthritis caused by uric acid crystals, known for sudden, severe attacks that often start in the big toe.
Bone & joint
4 guides
Avascular Necrosis
Death of bone tissue caused by a loss of blood supply, most often in the hip, which can lead to collapse of the joint.
Diffuse Idiopathic Skeletal Hyperostosis
A condition where ligaments along the spine turn into bone, causing stiffness, usually in people over 50.
Osteoarthritis
The most common form of arthritis, where cartilage breaks down and joints become painful and stiff, especially the knees, hips, hands and spine.
Osteoporosis
A condition of thin, fragile bones that raises the risk of fractures, often without any symptoms until a bone breaks.
Pain & other conditions
5 guides
Erythema Nodosum
Tender red lumps under the skin, usually on the shins, caused by inflammation of the fat layer.
Fibromyalgia
A long-term condition of widespread pain, fatigue and poor sleep caused by heightened pain processing in the nervous system.
Lyme Arthritis
Joint inflammation caused by the tick-borne bacterium Borrelia burgdorferi, usually a swollen knee weeks to months after infection.
Raynaud’s Phenomenon
Episodes where fingers or toes turn white or blue in the cold or with stress, caused by spasms of small blood vessels.
Viral Arthritis
Joint pain and swelling triggered by a viral infection, usually short-lived.
Educational information only. Your own care plan should come from your physician, who knows your full history.