All conditions

Vasculitis & polymyalgia

Giant Cell Arteritis

Also known as: Temporal arteritis, GCA

Inflammation of large arteries, especially in the head, that can cause sudden vision loss if not treated quickly. It occurs almost only after age 50.

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Giant Cell Arteritis
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Animated explainer

Artery wallLess blood reaches the organ
Step 1 of 4
How it works · Vasculitis
Blood flows freely

Healthy blood vessels have smooth, flexible walls and an open channel.

What it is

Giant cell arteritis inflames the walls of the aorta and its branches, most famously the temporal arteries at the sides of the head. Narrowed arteries can cut off blood supply to the eye. Many people also have polymyalgia rheumatica.

Symptoms

New headache, scalp tenderness, jaw pain when chewing, vision changes such as blurring, double vision or temporary loss, fever, fatigue and shoulder or hip stiffness.

How it’s diagnosed

ESR and CRP are usually high. Ultrasound of the temporal arteries, temporal artery biopsy or PET scan confirm the diagnosis. Testing should not delay treatment when vision is at risk.

Treatment

High-dose steroids are started immediately, then tapered over months. Tocilizumab helps keep the disease in remission and lowers total steroid exposure.

Living with it

New vision symptoms are an emergency: go to the ER. Long-term steroid use calls for bone protection and blood sugar and blood pressure checks.

At a glance

Category

Vasculitis & polymyalgia

Also known as

Temporal arteritis, GCA

Reviewed by Farhan Tahir, MD, FACR

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