All medications
Biologics
Sarilumab
Brand names: Kevzara
An IL-6 receptor blocker given as an injection every two weeks.
Video lesson
Animated explainer
What it’s used for
Rheumatoid arthritis and polymyalgia rheumatica.
How it works
It blocks the IL-6 receptor, cutting off one of the main inflammation signals.
How it’s taken
An injection under the skin every 2 weeks.
Side effects
Infections, low white counts, raised liver enzymes and cholesterol, and injection-site reactions.
Monitoring
Blood counts, liver tests and lipids, especially in the first months.
Good to know
Like tocilizumab, it can hide fever and lower CRP during infection.
At a glance
Class
Biologics
Brand names
Kevzara
Reviewed by Farhan Tahir, MD, FACR
Questions about your own care?
Book an in-person or telehealth consultation with Dr. Tahir.
For education only. Don’t start, stop or change a medicine without talking to your care team.