All medications
Bone health
Romosozumab
Brand names: Evenity
A bone-building antibody that both adds new bone and slows bone loss.
Video lesson
Animated explainer
What it’s used for
Postmenopausal osteoporosis at very high fracture risk.
How it works
It blocks sclerostin, a natural brake on bone formation, so osteoblasts build bone faster.
How it’s taken
Two injections under the skin once a month for 12 months.
Side effects
Joint pain, headache and injection-site reactions. A boxed warning for heart attack and stroke.
Monitoring
Calcium, and a review of heart and stroke history before starting.
Good to know
Followed by an antiresorptive medicine to keep the gains.
At a glance
Class
Bone health
Brand names
Evenity
Reviewed by Farhan Tahir, MD, FACR
Questions about your own care?
Book an in-person or telehealth consultation with Dr. Tahir.
For education only. Don’t start, stop or change a medicine without talking to your care team.