All medications

Biologics

Golimumab

Brand names: Simponi (injection), Simponi Aria (infusion)

A TNF inhibitor available as a monthly injection or an infusion every 8 weeks.

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Golimumab
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Animated explainer

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How it works · Blocking TNF
Immune cells release TNF

TNF is a chemical messenger. Overactive immune cells release it to call in more inflammation.

What it’s used for

Rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis and ulcerative colitis.

How it works

An antibody that binds TNF and switches off its signal.

How it’s taken

A monthly injection under the skin, or IV infusions at weeks 0 and 4, then every 8 weeks.

Side effects

Upper respiratory infections, injection reactions and a higher risk of serious infection.

Monitoring

TB and hepatitis B screening, then periodic labs.

Good to know

The monthly schedule suits people who prefer fewer injections.

← Certolizumab

Abatacept →

At a glance

Class

Biologics

Brand names

Simponi (injection), Simponi Aria (infusion)

Reviewed by Farhan Tahir, MD, FACR

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For education only. Don’t start, stop or change a medicine without talking to your care team.