All medications
Biologics
Certolizumab
Brand names: Cimzia
A TNF inhibitor with a structure that crosses the placenta very little.
Video lesson
Animated explainer
What it’s used for
Rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, Crohn’s disease and psoriasis.
How it works
A modified antibody fragment that binds TNF.
How it’s taken
An injection under the skin every 2 or 4 weeks.
Side effects
Injection-site reactions and a higher risk of infection, including TB reactivation.
Monitoring
TB and hepatitis B screening, then periodic labs.
Good to know
Often preferred for women who need TNF therapy during pregnancy and breastfeeding.
At a glance
Class
Biologics
Brand names
Cimzia
Reviewed by Farhan Tahir, MD, FACR
Questions about your own care?
Book an in-person or telehealth consultation with Dr. Tahir.
For education only. Don’t start, stop or change a medicine without talking to your care team.