All medications
Biologics
Etanercept
Brand names: Enbrel and biosimilars (Erelzi, Eticovo)
A TNF-blocking biologic used for inflammatory arthritis and psoriasis.
Video lesson
Animated explainer
What it’s used for
Rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis and psoriasis.
How it works
A receptor-based protein that soaks up TNF before it reaches cells.
How it’s taken
An injection under the skin once a week.
Side effects
Injection-site reactions, upper respiratory infections and a higher risk of serious infection.
Monitoring
TB and hepatitis B screening before starting, then periodic labs.
Good to know
Unlike some TNF inhibitors, etanercept is not used for inflammatory bowel disease or uveitis.
At a glance
Class
Biologics
Brand names
Enbrel and biosimilars (Erelzi, Eticovo)
Reviewed by Farhan Tahir, MD, FACR
Questions about your own care?
Book an in-person or telehealth consultation with Dr. Tahir.
For education only. Don’t start, stop or change a medicine without talking to your care team.