Video lesson
Animated explainer
What it’s used for
Psoriatic arthritis, psoriasis, Crohn’s disease and ulcerative colitis.
How it works
It neutralizes IL-23 so the inflammatory immune cells it supports settle down.
How it’s taken
An injection under the skin at weeks 0 and 4, then every 12 weeks.
Side effects
Colds, headache, fatigue and injection-site reactions. Liver tests are checked in bowel disease dosing.
Monitoring
TB screening, then routine follow-up.
Good to know
Only four injections a year once established.
At a glance
Class
Biologics
Brand names
Skyrizi
Reviewed by Farhan Tahir, MD, FACR
Questions about your own care?
Book an in-person or telehealth consultation with Dr. Tahir.
For education only. Don’t start, stop or change a medicine without talking to your care team.