All medications
Pain & symptom relief
Pregabalin
Brand names: Lyrica
A nerve-calming medicine used for fibromyalgia and nerve-related pain.
Video lesson
Animated explainer
What it’s used for
Fibromyalgia, diabetic and post-shingles nerve pain, and some other nerve pain conditions.
How it works
It reduces the release of pain-signaling chemicals from overactive nerves.
How it’s taken
Capsules taken once to three times a day, starting low and increasing gradually. A bedtime dose can also improve sleep.
Side effects
Dizziness, sleepiness, weight gain, swelling of the feet and blurred vision. It can affect driving and balance at first.
Monitoring
Kidney function guides the dose. Watch for mood changes, and tell your doctor about other sedating medicines.
Good to know
Avoid alcohol. Do not stop suddenly. Pregabalin is a controlled substance, so keep it secure.
At a glance
Class
Pain & symptom relief
Brand names
Lyrica
Reviewed by Farhan Tahir, MD, FACR
Questions about your own care?
Book an in-person or telehealth consultation with Dr. Tahir.
For education only. Don’t start, stop or change a medicine without talking to your care team.