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Pain & symptom relief

Joint Steroid Injections

Brand names: Triamcinolone (Kenalog, Zilretta), methylprednisolone (Depo-Medrol)

A corticosteroid injected directly into a joint, bursa or tendon sheath to calm local inflammation.

Video lesson

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Joint Steroid Injections
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How it works · Corticosteroids
Inflammation in many places

During a flare, inflammatory signals are active in many tissues at once.

What it’s used for

Inflamed joints in RA, PsA, gout, pseudogout and osteoarthritis flares, bursitis and tendon sheath inflammation.

How it works

A concentrated dose of steroid settles inflammation right where it is injected, with little reaching the rest of the body.

How it’s taken

A quick in-office injection, often with ultrasound guidance. Relief usually begins within days and can last weeks to months.

Side effects

Brief soreness, a short-lived flare, skin lightening at the site, and a temporary rise in blood sugar in people with diabetes. Infection is rare.

Monitoring

Most joints are limited to a few injections per year. People with diabetes should check blood sugar more often for a few days after.

Good to know

Rest the joint for a day or two afterward. Call your doctor if the joint becomes hot, very red or you develop a fever.

At a glance

Class

Pain & symptom relief

Brand names

Triamcinolone (Kenalog, Zilretta), methylprednisolone (Depo-Medrol)

Reviewed by Farhan Tahir, MD, FACR

Questions about your own care?

Book an in-person or telehealth consultation with Dr. Tahir.

For education only. Don’t start, stop or change a medicine without talking to your care team.